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Hydroxyapatite, calcium phosphate, <br>calcium sulfate, calcium silicate

XUPU BIOLOGY

Hydroxyapatite, calcium phosphate,
calcium sulfate, calcium silicate

Applied in multiple fields such as dentistry, orthopedics, and calcium supplementation health care

Learn more >

XUPU BIOLOGY

Hydroxyapatite, calcium phosphate,
calcium sulfate, calcium silicate

Applied in multiple fields such as dentistry, orthopedics, and calcium supplementation health care

Learn more >

XUPU BIOLOGY

Hydroxyapatite, calcium phosphate,
calcium sulfate, calcium silicate

Applied in multiple fields such as dentistry, orthopedics, and calcium supplementation health care

Learn more >

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Product Center

Mainly researching calcium sulfate and hydroxyapatite whisker materials, applied in dentistry, orthopedics, calcium supplementation and health care, and other fields.

Calcium sulfate for bone repair

Hydroxyapatite whisker material

Nano Hydroxyapatite

Calcium phosphate

Calcium silicate material

Calcium sulfate for bone repair

This material has good biocompatibility, can be completely degraded, does not cause foreign body irritation to surrounding tissues, can be injected into bone defects, and solidifies in situ. It is considered one of the most promising bone graft substitute materials.

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Hydroxyapatite whisker material

Hydroxyapatite, as a relatively mature bone repair material, has a chemical composition and structure similar to bone, with good biocompatibility and osteoinductivity.

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Nano Hydroxyapatite

The natural bone tissue of the human body can be regarded as a type of nanocomposite material, whose mechanical properties originate from the ordered mineralized structure of its organic and inorganic components.

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Calcium phosphate

Calcium phosphate is an inorganic compound with the chemical formula Ca3 (PO4) 2. It is a white crystalline or amorphous powder that is slightly soluble in water, easily soluble in dilute hydrochloric acid and nitric acid, and insoluble in ethanol, acetone, and ether. It is commonly used as an anti caking agent, acidity regulator, nutritional supplement (fortified calcium), fragrance enhancer, stabilizer, and water retention agent. It is also used as an acid making agent in medicine.

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Calcium silicate material

Calcium silicate, as an important inorganic non-metallic material, demonstrates extensive application value in various fields due to its excellent properties, especially gaining significant attention in biomedical areas such as bone repair.

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About Us

Professionally dedicated to the field of
calcium sulfate andhydroxyapatite whiskers

Xupu (Shanghai) Biotechnology Co., Ltd. was established in 2023. It is a company professionally dedicated to the field of calcium sulfate and hydroxyapatite whiskers, with a factory area of 66,600 square meters, a R&D technical team of 120 people, import and export to more than 40 countries, and more than 300 cooperative clients. It has rich industry experience, mainly researching calcium sulfate and hydroxyapatite whisker materials, applied in dentistry, orthopedics, calcium supplementation and health care, and other fields.

After years of development, the company's business services cover provinces and cities across the country, Hong Kong, Macao, Taiwan regions, and overseas. The number of service projects exceeds 50,000, with an annual sample testing throughput of over 500,000 cases. The served units include more than 2,500 universities, research institutes, hospitals, enterprises, among which there are over 360 top-tier hospitals. Professionally dedicated to the field of calcium sulfate and hydroxyapatite whiskers, with rich industry experience, mainly researching calcium sulfate and hydroxyapatite whisker materials, applied in dentistry, orthopedics, calcium supplementation and health care, and other fields.

A company professionally dedicated to the field of calcium sulfate and hydroxyapatite whiskers, with rich industry experience, mainly researching calcium sulfate and hydroxyapatite whisker materials, applied in dentistry, orthopedics, calcium supplementation and health care, and other fields. A company professionally dedicated to the field of calcium sulfate and hydroxyapatite whiskers, with rich industry experience, mainly researching calcium sulfate and hydroxyapatite whisker materials, applied in dentistry, orthopedics, calcium supplementation and health care, and other fields.

66600 ㎡

Factory Area

120 +

Technical Team

40 +

Import and Export Regions

300 +

Cooperative Clients

Application Fields

Applied in dentistry, orthopedics, calcium supplementation and health care, and other fields.

Dentistry

Applied to calcium phosphate series additive manufacturing slurries and high-end orthopedic implants to enhance the performance of biomedical materials.

Orthopedics

Bone repair materials (such as artificial bones and joint implants) promote bone tissue healing and also serve as drug carriers to control the drug release rate.

Calcium Supplement Health Care

Adding hydroxyapatite to calcium supplements can increase calcium absorption and bioavailability, helping to prevent diseases such as osteoporosis.

Global Network

Providing the best service to customers

From40 countries' 300 customers served

A diversified marketing model has established a complete sales and service system. Products are exported to more than 40 countries and regions including Europe and America, South America, Africa, Southeast Asia, the Middle East, Iran, Singapore, Greece, etc. We are committed to developing the enterprise with high-quality services and products.

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Blog Information

Follow Xupu for real-time updates

Hydrothermal synthesis of hydroxyapatite whiskers

Hydroxyapatite (HA) whiskers have a low dislocation density and high tensile properties, making them suitable as toughening materials for bioceramics. The experiment synthesized HA whiskers with high crystallinity and intact grains using calcium carbonate and calcium hydrogen phosphate as raw materials through a hydrothermal method. The crystal phase composition, morphology, and structure of HA were analyzed using XRD, SEM, and FT-IR. Additionally, the ζ potential and particle size distribution of the product were measured using a particle size and ζ potential analyzer. The results indicate that increasing the hydrothermal temperature promotes crystal growth along the c-axis; at 220°C for 10 hours, HA whiskers with an end diameter of 0.8 μm and length of 6 μm were obtained, with a small amount of carbonate entering the apatite structure. The dispersion of HA in ethylene glycol is more uniform and stable than in water, with an average powder particle size of about 2 μm.

Study on the Circularly Polarized Fluorescence Properties of Bacterial Cellulose

Cellulose is the most abundant and easily renewable resource in nature, and the effective utilization of this type of resource is undoubtedly green and economical. Among them, bacterial cellulose (BC) has advantages over cellulose from other sources, such as high purity, high crystallinity, and good biocompatibility, which has increasingly attracted researchers' interest. Bacterial cellulose has been widely applied in fields such as biomedicine, electrical materials, and optical materials. Meanwhile, circularly polarized light can contain and transmit richer information than ordinary light sources, thus attracting attention in many fields such as optical display devices, information encryption materials, biological coding, optical information storage, and optical devices. There have been many studies on the circular polarization properties of other forms of cellulose, especially crystalline nanocellulose, but the circular polarization properties of bacterial cellulose have not yet been reported.

2025-08-07

Hydrothermal synthesis of hydroxyapatite whiskers

2025-08-07

Study on the Circularly Polarized Fluorescence Properties of Bacterial Cellulose

2025-08-07

Preparation of Magnetic Hydroxyapatite Whiskers and Study of Their Magnetic Response Behavior under Magnetic Field

The orientation of hydroxyapatite whiskers (HAw) is one of the keys to designing and developing bioceramics. In this study, magnetic nanoparticles of magnetite (Fe3O4) were loaded onto the surface of HAw using a hydrothermal method, successfully preparing magnetic HAw composites with excellent magnetic response characteristics. The physicochemical and biological properties of the magnetized HAw were systematically studied, and its orientation behavior in a weak magnetic field was explored. The results showed that magnetite (Fe3O4) nanoparticles were successfully loaded onto the surface of HAw. The prepared magnetized HAw exhibited superparamagnetism at room temperature and had good magnetic response characteristics, which could be controlled using only a conventional permanent magnet. Combined with magnetic field-induced injection molding technology, the alignment direction imposed by the external magnetic field was effectively fixed. CCK-8 experimental results indicated that the magnetized HAw was not cytotoxic.

2025-08-07

Hydrothermal Preparation of Hydroxyapatite Whiskers and Study on Their Needle-like Growth Mechanism

Hydroxyapatite whiskers have good biocompatibility and mechanical properties, making them a biomedical material with broad application prospects. The hydrothermal synthesis of hydroxyapatite whiskers offers good reproducibility, ease of control, high crystallinity, uniform shape, and stable performance. Using self-made CaHPO_4 as the nutrient, hydroxyapatite whiskers were prepared by the hydrothermal method. The obtained whiskers were systematically tested and qualitatively analyzed. The effects of parameters such as temperature, heating rate, pH, pressure, filling degree, and nutrient on whisker growth under hydrothermal conditions were discussed. Various crystal defects formed during the whisker growth process were analyzed, and solutions were proposed. Additionally, the crystallography and interfacial kinetics mechanisms of the needle-like growth of hydroxyapatite whiskers were explored. Experimental results show that hydrothermal synthesis can produce needle-like hydroxyapatite whiskers with an average length of 1 mm and an aspect ratio of 60 to 80. It was found that temperature, heating rate, pH, pressure, and nutrients affect the solubility of CaHPO_4, thereby changing the supersaturation of the system and influencing the growth of hydroxyapatite whiskers. Low supersaturation and low pH favor the needle-like growth of hydroxyapatite whiskers. Analysis indicates that the mechanism of needle-like growth of hydroxyapatite whiskers is: on one hand, the number of Ca~(2+) connections to Ca-P_6O_(24) on the c-plane is higher than on the a and b planes, making the c-plane more stable and having a higher growth rate.

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Building 3, No. 139 Xuanqiu Road, Pudong New Area

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